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Clinical Investigations: CARDIOLOGY |

Early Exercise Training After Mitral Valve Repair*: A Multicentric Prospective French Study

Philippe Meurin, MD; Marie Christine Iliou, MD; Ahmed Ben Driss, MD, PhD; Bernard Pierre, MD; Sonia Corone, MD; Pascal Cristofini, MD; Jean Yves Tabet, MD; on behalf of the Working Group of Cardiac Rehabilitation of the French Society of Cardiology
Author and Funding Information

Affiliations: *From the Les Grands Prés (Drs. Meurin, Driss, and Tabet), Centre de Réadaptation Cardiaque de la Brie, Villeneuve Saint Denis; Service de Réadaptation Cardiaque (Drs. Iliou and Cristofini), Groupe Hospitalier Broussais-HEGP, Paris; Centre de Médecine Physique et de Réadaptation IRIS (Dr. Pierre), Marcy Etoile; and Hôpital de Bligny (Dr. Corone), Briis sous Forges, France.,  A list of participants is given in the Appendix.

Correspondence to: Philippe Meurin, MD, Les Grands Prés, Centre de Réadaptation Cardiaque de la Brie, 27 rue Sainte Christine, 77174 Villeneuve Saint Denis, France; e-mail: philippemeurin@hotmail.com



Chest. 2005;128(3):1638-1644. doi:10.1378/chest.128.3.1638
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Background: Surgical mitral valve (MV) repair is now the best technique to correct mitral regurgitation (MR). However, clinical studies have shown that without exercise training (ET), there is no significant postoperative exercise tolerance improvement. Moreover, healing duration of the MV wound is not well known; thus, the feasibility of an early ET program (ETP) may be discussed.

Objectives: To evaluate safety and feasibility of an early ETP after MV repair.

Methods and results: All patients hospitalized in 13 postoperative centers after MV repair from September 2002 to June 2003 were included in this prospective study. They underwent an ETP during 3 weeks on average. Transthoracic echocardiography and a cardiopulmonary exercise test were performed before and after the ETP.

Patients: Two hundred fifty-one consecutive patients (male gender, 70%; mean age, 59 ± 14 years [± SD]) were included 16 ± 10 days after MV repair. There was no MR occurrence or worsening after the ETP. Left ventricular ejection fraction slightly increased (53 ± 10% vs 55 ± 9%, p = 0.004). Peak oxygen consumption and anaerobic threshold increased from 16.3 ± 4.5 to 20.0 ± 6.0 mL/kg/min (22% increase) and from 12.2 ± 3.8 to 14.2 ± 4.3 mL/kg/min (16% increase) respectively, (p < 0.0001).

Conclusion: ET after MV repair does not deteriorate the outcome of recent surgery and seems efficient.

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