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Obstructing Tracheal Pulmonary Langerhans Cell Histiocytosis*

Zvi G. Fridlender, MD; Mendel Glazer, MD; Gail Amir, MD; Neville Berkman, MBBCh
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*From the Institute of Pulmonology (Drs. Fridlender and Berkman) and the Department of Pathology (Dr. Amir), Hadassah University Hospital, Jerusalem, Israel; and Rokah Pulmonary Institution (Dr. Glazer), Kupat Cholim Clalit, Israel.

Correspondence to: Zvi G. Fridlender, MD, Institute of Pulmonology, Hadassah University Hospital, PO Box 12000, Jerusalem, Israel; e-mail: Fridlender@hadassah.org.il



Chest. 2005;128(2):1057-1058. doi:10.1378/chest.128.2.1057
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Pulmonary Langerhans cell histiocytosis, also known as eosinophilic granuloma, is an uncommon interstitial lung disease. A solitary nodule, usually parenchymal, may rarely be the only manifestation of the disease. We describe a case of Langerhans cell histiocytosis presenting as an obstructing tracheal lesion in a 55-year-old woman. Following complete resection of the lesion via flexible bronchoscopy, full recovery was achieved. This case represents a unique cause for tracheal obstruction, as well as an unreported manifestation of pulmonary Langerhans cell histiocytosis.

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