0
Editorials |

Acute and Chronic Respiratory Failure in Patients With Obesity-Hypoventilation Syndrome : A New Challenge for Noninvasive Ventilation

Antoine Cuvelier, MD, PhD; Jean-François Muir, MD, FCCP
Author and Funding Information

Affiliations: Rouen, France
 ,  Drs. Cuvelier and Muir are from the Service de Pneumologie, Hôpital de Bois-Guillaume, Rouen, France.

Correspondence to: Antoine Cuvelier MD, PhD, Service de Pneumologie et Unité de Soins Intensifs Respiratoires, Hôpital de Bois-Guillaume, CHU de Rouen, 76031 Rouen CEDEX, France; e-mail: antoine.cuvelier@chu-rouen.fr



Chest. 2005;128(2):483-485. doi:10.1378/chest.128.2.483
Text Size: A A A
Published online

Extract

The increased prevalence of adult obesity has been one of the most striking epidemiologic phenomenon in most countries around the world during these last 100 years. It is also a matter of great concern in children 5 to 12 years old in whom the prevalence of obesity has been multiplied by three in the United States and by four in France between 1960 and 2000.1

Because adult obesity is a risk factor for obstructive sleep apnea syndrome (OSAS), obesity-hypoventilation syndrome (OHS), acute hypercapnic respiratory failure (AHRF), and higher incidence of respiratory postsurgical complications, it is not surprising to see that obesity is now considered as an emerging cause of chronic respiratory failure (CRF) requiring domiciliary ventilatory assistance.2 CRF in obese patients is a frequent issue in clinical practice and is usually diagnosed either in the context of an AHRF in the emergency department or when investigating a potential diagnosis of OSAS or even during a preoperative evaluation. Approximately 10% of patients with OSAS have daytime hypercapnia, often associated with pulmonary hypertension.3 Obstructive airways disease may be associated in some of these patients and constitutes the so-called overlap syndrome.46 Another clinical picture of CRF in obese patients is OHS,3 previously called the Pickwickian syndrome,7 which is associated with a range of different sleep respiratory patterns such as hypoventilation, obstructive apneas, central apneas, or a combination of these.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543