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Editorials |

Temporal Changes in Clinical Outcomes With ARDS

Greg S. Martin, MD, MSc
Author and Funding Information

Affiliations: Atlanta, GA
 ,  Dr. Martin is affiliated with the Division of Pulmonary, Allergy, and Critical Care Medicine, Emory University School of Medicine.

Correspondence to: Greg S. Martin, MD, MSc, Assistant Professor of Medicine, Emory University School of Medicine, 49 Jesse Hill Jr Dr SE, Atlanta, GA 30303; e-mail: Greg_Martin@emory.org



Chest. 2005;128(2):479-481. doi:10.1378/chest.128.2.479
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Acute lung injury (ALI) and ARDS are common and lethal conditions. The spectrum of lung injury represented by ALI/ARDS affects approximately 150,000 people each year in the United States,1 although the number may be much higher.2 The mortality rate associated with ALI/ARDS depends on the underlying cause, varying from < 20% for traumatically injured patients to > 60% for sepsis-induced ALI/ARDS. Crude estimates of the health-care costs associated with ALI/ARDS may exceed $5 billion per year in the United States alone.3 Substantial efforts have been devoted to finding effective therapies and improving clinical outcomes, and to date we have had limited, if any, success.46

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