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Editorials |

Does Lung Volume Reduction Surgery Really Improve Bone Mineral Density?

Robert James Cerfolio, MD, FCCP
Author and Funding Information

Affiliations: Birmingham, AL
 ,  Dr. Cerfolio is Associate Professor of Surgery, Chief of the Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, University of Alabama at Birmingham.

Correspondence to: Robert James Cerfolio, MD, FCCP, Division of Cardiothoracic Surgery, University of Alabama at Birmingham, 1900 University Blvd THT 712, Birmingham, AL 35295; e-mail: Rcerfolio@uab.edu



Chest. 2005;127(6):1878-1879. doi:10.1378/chest.127.6.1878
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Dr. Mieno and colleagues have presented a well-written and interesting article (see page 1960) concerning other potential benefits derived from lung volume reduction surgery (LVRS) besides improvement in dyspnea and pulmonary function test results. Prior to accepting the conclusion of any study, its methodology must be critically scrutinized and questioned.

The study by Mieno and colleagues is retrospective cohort study that spans a 4-year period. This lengthy time frame lends itself to treatment bias. It may introduce some biases since treatment strategies can change, but it is unlikely that many significant changes were made.

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