We read with great interest the recent case report in CHEST (September 2004)1by Norman et al, in which eosinophilic pneumonia preceded the establishment of rheumatoid arthritis (RA). We would like to add some comments to that precious case report. RA, a polarized disease of representative T helper (Th) type 1 cells, is less compatible with the coexistence of allergic disorders with a Th2 cytokine pattern than with other inflammatory diseases. However, previous studies2–3 have demonstrated the coexistence of Th2 diseases, such as bronchial asthma and atopic dermatitis, and Th1 diseases, such as RA, insulin-dependent diabetes mellitus, and celiac disease. Kero and colleagues3 have indicated that the presence of Th2 diseases in subjects with Th1 diseases may be related to environmental factors. The most recognized and important effector cells in Th2 diseases are eosinophils. We are, therefore, interested in the chemoattractant factors of eosinophils in the patient reported by Norman and colleagues.1 Immunohistochemical examinations of Th2 cytokines, including interleukin (IL)-4 and IL-5, and chemokines such as eotaxin in lung tissue specimens from the patient would provide further important information.