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Editorials |

Proton-Pump Inhibitor Therapy for Gastroesophageal Reflux Disease : Does It Treat the Asthma?

Subin Jain, MBBS, FCCP
Author and Funding Information

Affiliations: Louisville, KY
 ,  Dr. Jain is Assistant Professor of Medicine and Director, Adult Cystic Fibrosis Program, University of Louisville Health Sciences Center.

Correspondence to: Subin Jain, MBBS, FCCP, Section of Pulmonary Medicine, Veterans Affairs Medical Center, 800 Zorn Ave, Mail Code 111-i, Louisville, KY 40206; e-mail: subin.jain@louisville.edu



Chest. 2005;127(4):1097-1098. doi:10.1378/chest.127.4.1097
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The prevalence of gastroesophageal reflux disease (GERD) in patients with asthma has been shown to be between 30% and 80% in different studies.1 GERD has been implicated in a number of respiratory illnesses besides asthma, such as bronchitis, bronchiectasis, pneumonia, idiopathic pulmonary fibrosis, and, most recently, COPD.23 It is not entirely clear whether GERD contributes to the pathophysiology of asthma, occurs as a result of it, or perhaps is entirely incidental to the asthma symptoms. Nevertheless, many studies have identified the presence of GERD as an important factor in the poor control of asthma, and the treatment of GERD may improve respiratory symptoms.4

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