The Lung Biology series published by Marcel Dekker covers a wide range of topical issues. Some are collections of illuminating essays aimed at fellow researchers, while others target comprehensive coverage of their theme, in effect addressed “to whom it may concern.” No. 183, cast in the latter mold, is a detailed review of the epidemiology, pathology, physiology, presentation, and treatment of acute exacerbations of COPD (AECOPD). This is timely, in view of the current investment of time and effort that at long last is being directed toward the amelioration of this distressing group of conditions. In total, 66 contributors from 10 countries (11, if we count Scotland separately) have written all of 32 chapters. These are headed conventionally: definition, epidemiology, pathology, radiology, and so on.