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Editorials |

Inhaled Corticosteroids and Fracture Risk: Having Our Cake and Eating It Too

Robert Aris, MD; James F. Donohue, MD, FCCP; David Ontjes, MD
Author and Funding Information

Affiliations: Chapel Hill, NC
 ,  Dr. Aris is Associate Professor of Medicine and Medical Director of the Lung Transplant Program, University of North Carolina at Chapel Hill. Dr. Donohue is Professor of Medicine and Division Chief of Pulmonary Medicine, University of North Carolina at Chapel Hill. Dr. Ontjes is Professor of Medicine, University of North Carolina at Chapel Hill.

Correspondence to: Robert M. Aris, MD, CB# 7020, 420 Womack Building, Chapel Hill, NC 27599-7020



Chest. 2005;127(1):5-7. doi:10.1378/chest.127.1.5
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In this volume of CHEST (see page 89), Johannes et al have examined the risk of nonvertebral fracture related to inhaled corticosteroid (ICS) exposure among adults with chronic lung disease followed up in a managed-care setting. They found no increased fracture risk with any of this class of drugs and no dose-response curve. They concluded that “concern about nonvertebral fracture risk should not strongly influence the decision to use recommended doses of ICS in adults with chronic lung disease.” Studies of this type are very important to determine the role of ICSs in fractures. The authors should be credited for their diligent work.

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