The next two sections are where the strength of this book truly lies. These deal in depth with the basic aspects of tuberculosis, including host response. State-of-the-art information on the Mycobacterium genome project is the highlight of the section on “Genomics and Microbiology.” The microbiology of tuberculosis and the host response are well worth perusal by practicing physicians, who often tend to skip these chapters. I found the fourth and fifth sections, “Clinical Aspects” and “Therapy,” to be of particular interest, given my focus as a clinician, with all aspects of tuberculosis having been updated exhaustively. The chapters on “Pulmonary Tuberculosis” and “Imaging of Thoracic Tuberculous Infections” also deserve special mention. Although the chapter on “Tuberculosis and Silicosis” has been deleted, an abbreviated version has been incorporated into the chapter on “Pulmonary Tuberculosis.” However, the chapter “Hematologic Abnormalities and Mycobacterial Infections” has not found a place in this edition. With the change of name from “Pott’s Disease” to “Spinal Tuberculosis” in the second edition, this chapter, now bereft of the photographs that embellished it previously, appears less picturesque. However, the compendious chapters on extrapulmonary tuberculosis are laudable for their brilliant layout.