0
Editorials |

Nasal Nitric Oxide: Clue to a Diagnosis of Ciliary Dyskinesia

Philip E. Silkoff, MD, FCCP
Author and Funding Information

Affiliations: Wilmington, DE
 ,  Dr. Silkoff is Medical Director, AstraZeneca Pharmaceuticals, Wilmington, DE.

Correspondence to: Philip Silkoff, MD, FCCP, Medical Director, AstraZeneca Pharmaceuticals, DCC-2, 1800 Concord Pike, Wilmington, DE 19850-5437; e-mail: philip.silkoff@astrazeneca.com



Chest. 2004;126(4):1013-1014. doi:10.1378/chest.126.4.1013
Text Size: A A A
Published online

Extract

Primary abnormalities of ciliary structure and function, termed primary ciliary dyskinesia (PCD), are often diagnosed late in adult and pediatric patients presenting with respiratory tract manifestations such as bronchiectasis, sinusitis, or with infertility. Accurate diagnosis requires the suspicion of clinicians, and referral to a specialist center with expertise in assessing ciliary ultrastructure by electron microscopy, and performing ciliary function studies. While no cure is available, once diagnosed, careful attention can be directed to minimizing morbidity through measures such as bronchial clearance and prompt treatment of infection.1

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543