Cigarette smoking is without any doubt the leading cause of preventable death in the United States. The health-related economic loss associated with cigarette smoking is approximately $157 billion, and 440,000 premature deaths occur annually only in this country.1– Worldwide, 10 million people will die annually from tobacco-attributable diseases by 2030.2– Eighty percent of the particle products of Nicotiana tabacum liberated through a lit cigarette deposit in the tracheobronchial tree. At least 55 of the > 2,000 chemical compounds identified in the tobacco leaf are proven carcinogens.3 The epidemiologic evidence accumulated over almost 6 decades since the reports of Doll and Hill4–5 prove an association between smoking and lung cancer. Tobacco smoke has a causal role as well in the tragic worldwide epidemic of lung cancer. Tobacco products not only cause harm to the users, but nonusers are affected as well (environmental tobacco exposure).