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Lung Transplantation FREE TO VIEW

Maria L. Padilla, MD, FCCP
Chest. 2004;125(5):1968. doi:10.1378/chest.125.5.1968
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By Nicholas R. Banner, Julia M. Polak, and Magdi Yacoub, eds. Cambridge, UK: Cambridge University Press, 2003; 428 pp; $160

Lung Transplantation is a comprehensive, multiauthored book on lung transplantation that conveys the excitement and privilege of being involved in this heroic endeavor, and the anticipation of expected advances in lung transplantation science. The text is divided into three parts. The first part deals with individual pulmonary diseases that represent indications for transplantation. These conditions are appropriately discussed from the perspective of the issues and challenges that they present for transplantation. The second part reviews important aspects of lung and heart-lung transplantation with special attention to areas not often covered in general transplantation textbooks. These include anesthesia and intensive care management, hematologic considerations, and the growing field of pretransplantation psychodynamics as it affects posttransplantation care and survival. The final part encompasses state of the art reviews on tissue engineering, xenotransplantation, prospects for an artificial lung, and future directions.

In part one, the in-depth treatise on primary pulmonary hypertension contrasts with the more focused reviews of other entities, in which the discussions center on the disease as an indication for transplantation. This may account for the seemingly disparate quality of the initial chapters. There is also some redundancy in this part of the book that may be helpful to newcomers to the field but not to the seasoned, already-involved “transplantologist.” The reader will note several excellent chapters that are surely destined to serve as standard references, as they provide important insights into mechanisms of disease or great experiential knowledge. Most notable are those covering pulmonary hypertension, genetics and right ventricular function, explant and transplant pathology, immunologic mechanisms of graft injury, and transplant imaging. Other chapters provide sound advice on the evaluation and management of the transplant patient (eg, those on bronchiectasis, anesthesia and ICU care, and hematology). There is also an excellent discussion of similarities and differences in the practice of lung transplantation across several continents.

Lung Transplantation is primarily written for the medical transplant physician and for committed newcomers to the field. In addition to serving the usual functions of a textbook as an organized review of a field of study, this particular volume also represents an invaluable contribution to the practice of lung transplantation: the dissemination of knowledge gained by experienced centers, which is usually obtained only by the passage of years and the performance of substantial numbers of transplants. This text will also be of great help to practitioners in other disciplines (surgery, intensive care, pathology, cardiology, infectious diseases, nephrology, psychology, psychiatry) involved in the care of lung transplant patients or in the study of the science of transplantation.




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