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Empiric Therapy of Community-Acquired Pneumonia*: Guidelines for the Perplexed?

Burke A. Cunha, MD
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*From the Infectious Disease Division, Winthrop-University Hospital, Mineola, NY; and the State University of New York School of Medicine, Stony Brook, NY.

Correspondence to: Burke A. Cunha, MD, Chief, Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501



Chest. 2004;125(5):1913-1919. doi:10.1378/chest.125.5.1913
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This article discusses the key clinical aspects of empiric therapy of community-acquired pneumonia (CAP). Antibiotic selection, severity of CAP, single vs multiple pathogens, pharmacokinetic considerations, antibiotic resistance, IV vs oral antibiotic therapy for CAP, oral therapy for non-ICU hospitalized patients with CAP, β-lactams, macrolides, ketolides, doxycycline, respiratory quinolones, and pharmacoeconomic implications are discussed.


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