Of the remaining references, seven appear not to deal directly with asthma (refs 7–10,, 14,, 19,, 20
), seven are letters to the editor (refs 13–18
), one is an abstract (ref 3
), and one is a book authored by Drs. Lechin and van der Dijs (ref 2
). I cannot comment on their use of tianeptine in 20,000 patients with severe asthma, nor on its use in a national program to eradicate the disease in their country, for the book that they cite is not yet available to me. I am sure, however, that Drs. Lechin and van der Dijs would want to share with the rest of the medical world a treatment for asthma unfailingly successful. The usual way to share such information is through publishing in peer-reviewed journals large, controlled, prospective, blinded studies demonstrating efficacy. For such a remarkably effective treatment, this should be easy to accomplish. I, for one, would read such reports with the keenest interest.