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Occupational and Environmental Lung Disease |

Decreased Respiratory Symptoms After Intervention in Artificially Ventilated Offices in São Paulo, Brazil*

Gustavo S. Graudenz; Jorge Kalil; Paulo H. Saldiva; Maria do Rosário D. O. Latorre; Fabio F. Morato-Castro
Author and Funding Information

*From the Division of Allergy and Clinical Immunology, Internal Medicine Department (Drs. Graudenz, Kalil, and Morato-Castro), and Department of Pathology (Dr. Saldiva), School of Medicine; and Department of Epidemiology (Dr. Latorre), School of Public Health, University of São Paulo, São Paulo, Brazil.

Correspondence to: Gustavo S. Graudenz, MD, Rua Heitor Penteado 477, São Paulo, Brazil 05437–000; e-mail: gustavog@usp.br



Chest. 2004;125(1):326-329. doi:10.1378/chest.125.1.326
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Background: The increase in work-related respiratory complaints in artificially ventilated buildings have multiple causes, and intervention studies are a valuable approach to understanding possible mechanisms.

Study objectives: To analyze the effects of an intervention in a ventilation system with > 20 years of continuous use, and with a high rate of building-related respiratory complains.

Design: An epidemiologic study was done among individuals working in places with ventilation machinery and ducts with > 20 years of use, before and after intervention. Analysis of symptoms and logistic regression were performed to check the associations between air-conditioning intervention and reported symptoms.

Results: The air-conditioning intervention showed a protective effect on building-related worsening of respiratory symptoms (odds ratio, 0.132; 95% confidence interval, 0.030 to 0.575), naso-ocular symptoms (odds ratio, 0.231; 95% confidence interval, 0.058 to 0.915), and persistent cough (odds ratio, 0.071; 95% confidence interval, 0.014 to 0.356).

Conclusion: Intervention in high-risk occupational locations can be effective in improving perceived indoor air quality.

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