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Critical Care Reviews |

Pancreatitis-Associated Acute Lung Injury*: New Insights

Catherine M. Pastor; Michael A. Matthay; Jean-Louis Frossard
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*From the Département de Radiologie (Dr. Pastor), Division de Gastro-entérologie (Dr. Frossard), Hôpitaux Universitaires de Genève, 1211 Geneva 14, Switzerland; and Cardiovascular Research Institute (Dr. Matthay), University of California, San Francisco, CA.

Correspondence to: Catherine M. Pastor, MD, PhD, Laboratoire de Physiopathologie Hépatique et Imagerie Moléculaire, Bâtiment C - Room 6-795, Hôpital Cantonal Universitaire de Genève, Rue Micheli-du-Crest, 24, 1211 Geneva 14, Switzerland; e-mail: Catherine.Pastor@hcuge.ch



Chest. 2003;124(6):2341-2351. doi:10.1378/chest.124.6.2341
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The ARDS is an important cause of mortality in critically ill patients. Its exact incidence is unknown but may be as high as 75 per 100,000 population in the United States.1 The risk factors for developing this syndrome include pneumonia, gastric aspiration, sepsis, shock, and multiple transfusions, as well as less common causes such as multiple trauma, multiple fractures, cardiopulmonary bypass, drug overuse, and acute pancreatitis. Although acute pancreatitis represents one of the less common clinical disorders associated with ARDS, severe attacks of pancreatitis are frequently associated with acute lung injury and respiratory failure.2

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