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Editorials |

Drug Therapy for Pulmonary Arterial Hypertension : What’s on the Menu Today?

Sanjay Mehta
Author and Funding Information

Affiliations: London, ON, Canada
 ,  Dr. Mehta is Associate Professor of Medicine, Vascular Biology Group, Lawson Health Research Institute, London Health Sciences Centre, University of Western Ontario. Dr. Mehta has received consulting and speaking fees (Glaxo-Burroughs-Wellcome, Actelion Pharmaceuticals), and clinical investigator fees (Actelion, Pfizer, Encysive) from firms that own, market, and distribute pharmaceutical agents for PAH.

Correspondence to: Sanjay Mehta, MD, FCCP, Division of Respirology, London Health Sciences Center, Victoria South St Campus, 375 South St, London, ON, Canada, N6A 4G5; e-mail: sanjay.mehta@lhsc.on.ca



Chest. 2003;124(6):2045-2049. doi:10.1378/chest.124.6.2045
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Pulmonary arterial hypertension (PAH) is a clinical hemodynamic syndrome characterized by elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance in the absence of left-sided heart disease, lung disease, or pulmonary thromboembolic disease.12 PAH can be idiopathic (primary pulmonary hypertension [PPH]) or familial, and can arise in association with connective tissue diseases (CTDs), infection with the HIV, portal hypertension, and congenital heart disease (CHD).

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