Of a total of 820 medical students (93.2% of enrolled students) and 250 nursing students (89.3% of enrolled students) surveyed, 397 medical students (48.4%) and 126 nursing students (50.4%) returned a completed, legible survey; the response rate was not statistically different. Among the medical students, the median age was 24 years, 212 students (53.4%) were women, nearly 80% were white, 3% were African American, and 14% were Asian. One hundred five nursing students (83.3%) were women, with a median age of 25 years; approximately 70% were white, 13% were African American, and 7% were Asian. As expected, there were significantly more women in the nursing student sample compared to the medical student population (χ2 = 35.89, degrees of freedom [df] = 1, p < 0.001). Also, the ethnic distribution differed between the two groups; the nursing students had significantly higher proportion of African-American individuals and fewer Asians and whites compared to medical students (χ2 = 29.63, df = 2, p < 0.001). Female smokers had higher mean FTND score (3.67 ± 1.76) than male smokers (2.37 ± 0.82) [t = 2.83, p < 0.01]. Women also smoked more cigarettes per day (14.4) than men (9.3) [t = 1.94, p < 0.05], and reported smoking more often (t = 2.21, p < 0.05) and sooner (t = 2.75, p < 0.01) after waking up in the morning. Women also found that morning cigarettes were difficult to give up (t = 2.08, p < 0.05); however, there were no gender differences in smoking despite being ill, smoking in forbidden places, the duration of smoking, quit attempts, or plans to quit. There were no significant associations of FTND scores with age (r = 0.11, p > 0.05), or ethnic background (χ2 = 1.32, df = 2, p > 0.05) of smokers.