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Editorials |

Encouraging News From the Antibiotic Resistance Front

Nathan C. Dean
Author and Funding Information

Affiliations: Salt Lake City, UT
 ,  Dr. Dean is Adjunct Professor of Medicine, University of Utah, and has received honoraria during the past 5 years from Pfizer, Abbott, Ortho-McNeil, Bristol Myers Squibb, Roche, Glaxo Smith Kline, Bayer, Elan, Chiron, and Merck. Dr. Dean has also served on advisory boards for Roche, Bayer, GlaxoSmithKline, and Bristol-Myers Squibb. Unrestricted grants for research have come to the Deseret Foundation, Salt Lake City, under Dr. Dean’s name from Roche, Pfizer, and Bristol-Myers Squibb.

Correspondence to: Nathan C. Dean, MD, FCCP, Intermountain Health Care, 333 South Ninth East, Salt Lake City, UT 84102; e-mail: slndean@ihc.com



Chest. 2003;124(2):423-424. doi:10.1378/chest.124.2.423
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Streptococcus pneumoniae is the most common pathogen isolated from patients with community-acquired pneumonia,12 and also causes the most deaths.3 Resistance to multiple antibiotics has been rising among pneumococcal isolates over the past 20 years, leading to treatment failures and increased costs.46 Studies repeatedly have linked antibiotic consumption to antibiotic resistance, with the greatest resistance observed in noninvasive isolates from children. Children may be vectors for resistant pneumococci, given evidence for transmission of strains within families.7 Antibiotics not prescribed for younger children (doxycycline and fluoroquinolones) have been slower to develop resistance than macrolides and β-lactams used to treat childhood infections.8

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