We undertook this study to determine whether measurement of Spo2 by a newer and widely used model of pulse oximeter (Biox 3740; Ohmeda; Louisville, CO) is affected by various fingernail polish colors. Ten different colors of Wet ‘n’ Wild (Pavion; Nyack-on-the-Hudson, NY) fingernail polish were used: red, yellow, dark blue, green, black, purple, fuchsia, light blue, brown, and white. In seven healthy subjects, each finger of the left hand was painted with a fingernail polish while the fingers on the right hand remained unpainted. Three readings were taken from each finger with the probe in the standard position (top-to-bottom, Fig 1
, top, A) and in a side-to-side position (Fig 1
, bottom, B).3
The procedure was repeated with the next set of five colors after removal of the original set of colors. Combined measurements from the seven subjects were averaged, SEM calculated, and statistical significance determined by analysis of variance.