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Laboratory and Animal Investigations |

Efficacy of a New Intraaortic Propeller Pump vs the Intraaortic Balloon Pump*: An Animal Study

André Dekker; Koen Reesink; Erik van der Veen; Vincent van Ommen; Gijs Geskes; Cecile Soemers; Jos Maessen
Author and Funding Information

*From the Departments of Cardio Thoracic Surgery (Mssrs. Dekker and Reesink, and Drs. van der Veen, Geskes, Soemers, and Maessen) and Cardiology (Dr. van Ommen), Cardiovascular Research Institute Maastricht, Academic Hospital Maastricht, the Netherlands.

Correspondence to: Erik van der Veen, PhD, Department of Cardio Thoracic Surgery, Academic Hospital Maastricht, P. Debyelaan 25, 6229HX, Maastricht, the Netherlands; e-mail: erik.vanderveen@ctc.unimaas.nl



Chest. 2003;123(6):2089-2095. doi:10.1378/chest.123.6.2089
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Objective: To compare the efficacy of a new intraaortic propeller pump (PP) to provide hemodynamic support to the intraaortic balloon pump (IABP) in an acute mitral regurgitation (MR) animal model.

Background: A new intraaortic PP (Reitan catheter pump; Jomed; Helsingborg, Sweden) recently has been introduced. The pump’s aim is a reduction in afterload via a deployable propeller that is placed in the high descending aorta and can be set at rotational speeds of ≤ 14,000 revolutions per minute (rpm).

Methods: In nine calves, acute MR was created by placing a vena cava filter in the mitral valve. The PP was tested at 6,000, 10,000, and 14,000 rpm and was compared to 1:1 IABP support. Cardiac output, coronary blood flow, carotid artery flow, ascending and abdominal aortic pressure, left atrial pressure, and LV pressure-volume loops were recorded.

Results: The PP caused an rpm-dependent reduction in the mean ascending aortic pressure reaching −10 mm Hg (p < 0.05) at 14,000 rpm. However, mean (± SD) cardiac output did not improve (2.6 ± 0.7 to 2.5 ± 1.1 L/min; p = not significant), and mean diastolic coronary flow and carotid flow (47 ± 16 to 35 ± 15 centiliters/min, p < 0.05) were reduced. The IABP improved cardiac output, and carotid and diastolic coronary flow.

Conclusions: In this acute MR animal model, the PP reduced afterload but left out positive effects on cardiac output, which resulted in reduced perfusion of the upper body and the coronary circulation. Therefore, the IABP gives better hemodynamic support than the new PP in calves with acute MR.

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