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Clinical Investigations: TUBERCULOSIS |

The Effect of Pulmonary Rehabilitation in Patients With Post-tuberculosis Lung Disorder*

Morihide Ando; Atsushi Mori; Hiroshi Esaki; Tsuyoshi Shiraki; Hiroyuki Uemura; Mitsushi Okazawa; Hiroki Sakakibara
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From the Division of Respiratory Medicine and Clinical Allergy (Drs. Ando, Okazawa, and Sakakibara), Department of Internal Medicine, Fujita Health University, Aichi, Japan; and the Akutami Clinic (Drs. Mori, Esaki, Shiraki, and Uemura), Gifu, Japan.

Correspondence to: Morihide Ando, MD, Department of Internal Medicine, National Kinki-Chuo Hospital for Chest Diseases, 1180 Nagasone-cho, Sakai, Osaka, 591-8555, Japan; e-mail: m-ando@kch.hosp.go.jp



Chest. 2003;123(6):1988-1995. doi:10.1378/chest.123.6.1988
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Study objectives: Although the benefit of pulmonary rehabilitation (PR) has been demonstrated for patients with COPD, the benefit for patients with non-COPD lung disorders is still unclear. In the present study, we compared the effect of PR on patients with post-tuberculosis (TBC) lung disorders and patients with COPD.

Design: We performed a prospective nonrandomized open trial over a 9-week period.

Patients and methods: Thirty-two patients with post-TBC lung disorders (thoracoplasty, 25 patients; mean [± SD] age, 71 ± 5 years; FEV1, 0.84 ± 0.29 L) and 32 age-matched and FEV1-matched COPD patients were enrolled in the study. First, we compared the exercise tolerance between groups using a 6-min walking test. Next, we trained the patients using a 9-week outpatient PR program. We assessed improvement using clinical dyspnea ratings, a daily activity score, and the results of a 6-min walking test.

Results: When age and FEV1 were matched, the distance covered during the 6-min walking test did not differ between the groups. After rehabilitation, significant improvement was observed in both the post-TBC group and the COPD group in terms of Medical Research Council dyspnea grade, transition dyspnea index, activity score, and 6-min walking distance (42 m [p < 0.01] vs 47 m [p < 0.01], respectively). The magnitudes of the improvement in these parameters were comparable between the groups.

Conclusions: PR is as beneficial in post-TBC lung disorder patients as in COPD patients if the severity of the disability is similar.

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