0
Editorials |

Induced Sputum Analysis For T Helper Type 2 Cell Regulation : Closing the Loop

Frédéric F. Little; David M. Center
Author and Funding Information

Affiliations: Boston, MA
 ,  Dr. Little is an Instructor in Medicine and Dr. Center is Gordon and Ruth Snider Professor of Pulmonary Medicine and Chief, Division of Pulmonary, Allergy, and Critical Care Medicine, The Pulmonary Center, Boston University Medical Center.

Correspondence to: Frédéric F. Little, MD, Division of Pulmonary, Allergy, and Critical Care Medicine, The Pulmonary Center, Boston University Medical Center, 715 Albany St, Boston, MA 02118



Chest. 2003;123(6):1786-1788. doi:10.1378/chest.123.6.1786
Text Size: A A A
Published online

Extract

The past decade has seen notable progress in our understanding of allergic asthma. Despite clear advances in dissecting the molecular and genetic factors that contribute to the asthmatic phenotype, morbidity and mortality from asthma, especially in industrialized nations, is increasing.12 However, there is cause for optimism in the development of new diagnostics and therapeutics. The application of techniques in molecular biology, specifically the investigation of the control of gene transcription, has become routine and accessible. With these applications, we have greater understanding of the early steps in the development of the immune response that is central to expression of the asthmatic phenotype.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543