Many years ago Hippocrates stated, “In whatever disease sleep is laborious, it is a deadly symptom; but if sleep does good, it is not deadly.” Today, a potential role for sleep disorders in the pathogenesis and complications of cardiovascular disorders is a concept that has gained support.1–2
Specifically, several studies3–4
have been performed in order to analyze the underlying mechanisms and the clinical importance, as well as the effects and consequences of sleep apnea in patients with heart failure. In this issue of CHEST (see page 1536), the article by Sin et al from Toronto reports on the relationship of systolic BP to obstructive sleep apnea in patients with heart failure. Before discussing their findings in detail, we briefly summarize our knowledge regarding the association of sleep apnea, heart failure, and hypertension.