0
Articles |

β2-Adrenergic Receptor Polymorphisms in Children With Status Asthmaticus*

Saeed Binaei, BS; Michael Christensen, PhD; Cathy Murphy, RN; Qing Zhang, BS; Michael Quasney, MD, PhD
Author and Funding Information

*From the Departments of Clinical Pharmacy (Mr. Binaei and Dr. Christensen) and Pediatrics (Mr. Zhang and Dr. Quasney), Children's Foundation Research Center, University of Tennessee, Memphis, TN; LeBonheur Children's Medical Center (Ms. Murphy), Memphis, TN.

Correspondence to: Michael Quasney, MD, PhD, College of Medicine, Department of Pediatrics, 50 North Dunlap, Memphis, TN 38103; e-mail: mquasney@utmem.edu



Chest. 2003;123(3_suppl):375S. doi:10.1378/chest.123.3_suppl.375S
Text Size: A A A
Published online

Extract

Genetic polymorphisms within the gene coding for the β2-adrenergic receptor have been identified that influence cell signaling and down-regulation. The Gly/Gly polymorphism at position 16 is associated with increased airway hyperactivity, while the Glu/Glu polymorphism at position 27 is associated with decreased airway hyperactivity. We tested the hypothesis that children with status asthmaticus have genetic polymorphisms that are associated with increased airway hyperactivity.

First Page Preview

View Large
First page PDF preview

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543