Patients with infected bronchogenic carcinoma typically respond clinically and radiographically to proper antibiotic treatment based on cultures and sensitivities. In a series of nine patients with infected, undiagnosed lung cancer, “roentgenographic improvement” was noted in all patients.1 Specific radiographic changes in such patients, however, have not been evaluated. In this case, CT showed decreasing size of the infected tumor (> 1 cm decrease in diameter) and resolution of mediastinal lymphadenopathy following administration of antibiotics (Fig 3
). In patients with benign lung abscess, radiologic improvement with antibiotic treatment occurs in nearly all patients, with the majority having complete resolution of cavities within 3 months of presentation.,11 It is interesting to note that lung cancers may require restaging following antibiotic therapy if the tumor shrinks in size and/or the lymphadenopathy resolves. Prior to treatment with antibiotics, this patient’s cancer would have been staged as IIIA (T2N2M0); after antibiotics, the patient’s cancer was stage IB (T2N0M0).