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Introduction to Remodeling and Repair in Respiratory Diseases* FREE TO VIEW

JeanClare Seagrave
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*From the Lovelace Respiratory Research Institute Annual Symposium on Remodeling and Repair in Respiratory Diseases.

Correspondence to: JeanClare Seagrave, Lovelace Respiratory Research Institute, 2425 Ridgecrest SE, Albuquerque, NM 87108; e-mail; jseagrav@lrri.org

Chest. 2002;122(6_suppl):271S. doi:10.1378/chest.122.6_suppl.271S
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This special issue of CHEST is a compilation of articles provided by the speakers at a recent meeting organized by the Lovelace Respiratory Research Institute. The meeting, which focused on “Remodeling and Repair in Respiratory Diseases,” was held at the historic La Fonda Hotel in Santa Fe, New Mexico, on October 14–17, 2001. Despite concerns about travel resulting from the terrorist acts on September 11, 2001, the meeting was attended by over 150 scientists from 12 countries.

Respiratory diseases account for one death in four in the United States. Unlike many other high-impact diseases, such as heart disease and cancer, the incidence of many respiratory diseases, such as asthma and COPD, is increasing. Environmental factors are thought to be involved in many of these diseases, but except for the obvious impact of cigarette smoking, the exact factors and their mechanisms of action are still largely unknown. Although some progress has been made in treating these disorders, therapy is largely still supportive. Little is known about the processes responsible for the remodeling involved in the physiologic changes, nor do we know much about mechanisms that could be stimulated to effect repair of the damage. This meeting focused on the structural changes and their functional consequences as they occur in ARDS, asthma, pulmonary hypertension, fibrosis, neonatal diseases, and COPD. Each session of the symposium featured invited presentations by experts in their respective fields, complemented by poster presentations contributed in response to a call for abstracts.

This meeting was the fourth in a series sponsored by Lovelace Respiratory Research Institute. The topic of the 2002 meeting was “Molecular Approaches to the Early Diagnosis and Treatment of Respiratory Diseases,” held at the same location on October 13–16, 2002. More information is available at the symposium website: www.lovelace-symposium.org.




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