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Editorials |

Women and Mesothelioma

Dorsett D. Smith, MD, FCCP
Author and Funding Information

Affiliations: Everett, WA
 ,  Dr. Smith is Clinical Professor of Medicine, Division of Pulmonary Disease and Critical Care, Department of Medicine, University of Washington.

Correspondence to: Dorsett D. Smith, MD, FCCP, 4310 Colby Ave, Everett, WA 98203; e-mail: chestdis@ix.netcom.com



Chest. 2002;122(6):1885-1886. doi:10.1378/chest.122.6.1885
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In this issue of CHEST (see page 2224), Metintas and coworkers compared the relative risk of women vs men for a malignant pleural mesothelioma (MPM) due to environmental amphibole asbestos exposure. The relative risk was higher for women than for men: 159.8 per 100,000 vs 114.8 per 100,000, respectively. A previous study from a different area of Turkey called Karain Village, where there had been environmental exposure to a highly carcinogenic fibrous zeolite called erionite, also demonstrated a female sex predilection for MPM with a risk ratio of 440.9 per 100,000 for women vs 298.1 per 100,000 for men.1 North American, Australian, and European cohorts have always shown a much lower risk for women.24 Why the difference?

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