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Clinical Measurement of Pulmonary Edema

Michael A. Matthay, MD, FCCP
Author and Funding Information

Affiliations: San Francisco, CA
 ,  Dr. Matthay is Professor of Medicine and Anesthesia and Senior Associate of the Cardiovascular Research Institute at the University of California at San Francisco.

Correspondence to: Michael A. Matthay, MD, FCCP, Cardiovascular Research Institute, University of California, San Francisco, 505 Parnassus Ave, M917, Box 0624, San Francisco, CA 94143-0624; e-mail: mmatt@itsa.ucsf.edu



Chest. 2002;122(6):1877-1879. doi:10.1378/chest.122.6.1877
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Extract

Pulmonary edema is an important cause of acute respiratory failure in critically ill patients. In patients with acute myocardial infarction or with exacerbations of chronic left heart failure, pulmonary edema is often a major complication, leading to arterial hypoxemia and the need for treatment in an ICU setting. In some patients, assisted ventilation is required either with noninvasive ventilation or with positive-pressure ventilation via an endotracheal tube. Pulmonary edema also is a cardinal feature of clinical acute lung injury (ALI) and ARDS, resulting from an increase in lung vascular permeability with exudation of protein-rich edema fluid into the interstitium and distal air spaces of the lung.1

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