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Editorials |

The Changing Landscape of HIV-Related Lung Disease in the Era of Highly Active Antiretroviral Therapy

Kevin M. O’Neil, MD, FCCP, CAPT MC USN
Author and Funding Information

Affiliations: Bethesda, MD
 ,  Dr. O’Neil is the Director for Graduate Medical Education, National Naval Medical Center

Correspondence to: Kevin M. O’Neil, MD, FCCP, CAPT MC USN, Pulmonary Clinic, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600; e-mail: kmoneil@bethesda.med.navy.mil



Chest. 2002;122(3):768-771. doi:10.1378/chest.122.3.768
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No physician in the past 20 years is likely to have escaped the impact of HIV/AIDS infection on the practice of medicine. As we enter the third decade of the AIDS epidemic, the human toll is staggering. As of June 2001, almost 800,000 patients in the United States have developed AIDS. Over half of these have died, the overwhelming majority under age 45.1 Over 900,000 people are estimated to be living with HIV infection.2 Worldwide, the statistics are even more sobering. As of December 2001, there were more than 40 million people infected with HIV, most living in sub-Saharan Africa and Asia. Over 22 million people have died, including 3 million in 2001 alone.2 In parts of southern Africa, the prevalence of HIV infection in pregnant women exceeds 30%. HIV/AIDS has reduced life expectancy by one third in several sub-Saharan African countries, and it is now the fourth leading cause of death worldwide. Cases continue to accumulate, with an estimated 5 million new infections in 2001.2

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