There is an even balance between basic science and clinical study, including animal and human data. Selected sections of this book would appeal to the basic researcher, the pharmacologist, or the clinician. Each topic, however, is conveyed in an overview format so that one does not get too lost in molecular biology, pharmacokinetic formulas, or clinical disease monitoring. Appropriate graphs, tables, and figures complement the text and enhance its readability so that it would be useful to a varied audience. This book nicely outlines the basic mechanism for corticosteroid action, from glucocorticoid receptor gene regulation to blocking inflammatory chemokine expression. For clinicians, the overview of delivery devices and drug/patient determinants in bioavailability and side effects are helpful in providing a rationale for drug selection. Combination therapy for asthma is also covered. The final aspect of the book deals with future research into “soft steroids” and other molecular targets, such as nuclear transcription factors, in hopes of finding newer therapies with fewer side effects to make an impact on this disease. There is a slight bias to be more in-depth with budesonide over other corticosteroids, but that is reflective of the authors’ work with this drug. There is also some duplication of steroid side effects, with three chapters discussing variations on the theme.