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Pleural Nodularity in a Patient With Pyrexia of Unknown Origin*

Peter B. Wold, MD; Michael A. Farrell, MD
Author and Funding Information

*From the Department of Radiology, Mayo Clinic, Rochester, MN.

Correspondence to: Michael A. Farrell, MD, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55902; e-mail: farrell.michael@mayo.edu



Chest. 2002;122(2):718-720. doi:10.1378/chest.122.2.718
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A 26-year-old man with a history of intermittent fever of unknown etiology for the past 1.5 years presented to our institution with a 2-day history of fever, night sweats, and myalgias. His medical history was unremarkable except for a laparotomy at the age of 6 years following an accidental gunshot wound to the abdomen. He admitted having a previous blood transfusion and recreational use of cocaine and marijuana. Physical examination revealed a depressed affect and multiple skin tattoos, but findings were otherwise negative. CBC count demonstrated a mild leucocytosis (13.6 ×109/L; normal range, 3.4 to 10 × 109/L) and associated lymphocytosis (6.2 × 109/L; normal range, 0.9 to 2.9 × 109/L). Results of extensive laboratory testing (infection, immunology, and biochemistry) were otherwise unrevealing. The appearance of an abnormality on the chest radiograph (Fig 1 ) led to a CT study (Fig 2 ) and a possible biopsy because of concerns about underlying malignancy. The CT findings prompted another diagnostic study (Fig 3 ), and so the biopsy was canceled.

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