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Editorials |

Balancing Self and Patient in the Physician-Patient Relationship

Henry S. Perkins, MD
Author and Funding Information

Affiliations: San Antonio, TX
 ,  Dr. Perkins is Professor Department of Medicine, The University of Texas Health Science Center at San Antonio.

Correspondence to: Henry S. Perkins, MD, Department of Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229-3900



Chest. 2002;121(4):1019-1021. doi:10.1378/chest.121.4.1019
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In this issue of CHEST (see page 1337), Miller and Shorr examine the ethics of clinical trials funded by pharmaceutical companies and performed by practicing physicians. The authors describe a seven-point framework for evaluating the ethical soundness of any clinical trial. Then they use that framework to critique a recent company-sponsored study1 comparing a new inhaled corticosteroid, a proven inhaled corticosteroid, and a placebo for treating moderate persistent asthma. Miller and Shorr argue convincingly that, by withdrawing patients with stable asthma from proven treatment and randomizing some to placebo this study risked patients’ serious clinical deterioration.

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