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Editorials |

Prevention of Ventilator-Associated Pneumonia : Selecting Interventions That Make a Difference

Manuel Iregui, MD; Marin H. Kollef, MD, FCCP
Author and Funding Information

Affiliations: St. Louis, MO
 ,  Dr. Iregui is a Fellow, and Dr. Kollef is Associate Professor, Pulmonary and Critical Care Division, Washington University School of Medicine.

Correspondence to: Marin H. Kollef, MD, Washington University School of Medicine, Campus Box 8052, 660 South Euclid Ave, St. Louis, MO 63110; e-mail: kollefm@msnotes.wustl.edu



Chest. 2002;121(3):679-681. doi:10.1378/chest.121.3.679
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In this issue of CHEST (see page 858), Smulders et al describe the results from their randomized trial of intermittent subglottic drainage for the prevention of ventilator-associated pneumonia (VAP). They found that general ICU patients receiving intermittent subglottic drainage had a significantly lower incidence of VAP compared to patients in their control group (4% vs 16%; p = 0.014). The duration of mechanical ventilation, length of stay in the ICU and hospital, and mortality were similar for both groups.

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