Objectives: To compare CT virtual bronchoscopy (VB) to
CT alone and to conventional bronchoscopy for evaluation of central
airway stenoses in patients with Wegener’s granulomatosis.
Design: Prospective observer study, in which 18
thin-section helical CT scans of the trachea and bronchi of 11 patients
with Wegener’s granulomatosis were obtained. VB was performed using
surface rendering and was evaluated by one bronchoscopist and one
radiologist in a blinded fashion. Bronchoscopic correlation within an
average of 1.8 days of CT was available.
results: VB displayed 188 of 198 bronchi (95%). Thirty-two of 40
stenoses (80%) were detected by VB by at least one of two physicians
(double reading), and 22 of 40 stenoses (55%) were detected by a third
physician reading only the CT.
Conclusions: VB depicts
bronchi to the segmental level and detects the majority of central
airway stenoses in patients with Wegener’s granulomatosis. A team
approach is useful to attain optimal clinical benefit from VB for these