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Editorials |

Severe Community-Acquired Pneumonia : The Need To Customize Empiric Therapy

Richard G. Wunderink, MD, FCCP; Grant W. Waterer, MBBS, FCCP
Author and Funding Information

Affiliations: Memphis, TN 
 ,  Perth, Western Australia 
 ,  Dr. Wunderink is Director of Clinical Research, Methodist Le Bonheur Healthcare, and Dr. Waterer is Senior Lecturer in Respiratory Medicine, Department of Medicine, University of Western Australia, Royal Perth Hospital.

Correspondence to: Richard G. Wunderink, MD, FCCP, Methodist Le Bonheur Healthcare, 1265 Union Ave, 501 Crews Wing, Memphis, TN 38104-2499; e-mail: wunderiR@methodisthealth.org



Chest. 2001;120(4):1053-1055. doi:10.1378/chest.120.4.1053
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Even with extensive diagnostic regimens, most studies of community-acquired pneumonia (CAP) fail to determine the etiology in ≥ 50% of cases. In usual clinical practice, the diagnostic rate is closer to 15%, which results in most patients with CAP receiving an empiric antibiotic regimen rather than individualized therapy. The choice of empiric antibiotic agents is often guided by consensus guidelines.12 These guidelines are in turn based on covering the majority of pathogens identified in published findings from groups of patients with CAP.

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    Print ISSN: 0012-3692
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