Objective: To determine the incidence of subtypes of
pulmonary emphysema (PE) identified by CT imaging in male patients who
have a significant smoking history.
setting: We reviewed 945 subjects (619 men and 326 women) who had
undergone CT scanning. However, only the data for male subjects were
analyzed due to there being too few female subjects. The male subjects
were divided into the following two age groups: group A (age, ≤ 50
years) and group B (> 50 years). There were two subtypes of PE found:
centrilobular emphysema (CLE) and paraseptal emphysema (PSE). Based on
these subtypes, PE was divided into the following three categories: I
(CLE or CLE-predominant); II (CLE and PSE of equal extent); and III
(PSE or PSE-predominant).
Results: PE was found in 270
of 516 male smokers (10 of 38 female smokers had PE). Among male
subjects, in age group A there were 53 subjects with some degree of PE
(category I, 12 subjects [22.6%]; category II, 7 subjects[
13.2%]; and category III, 34 subjects [64.2%]). Among men in age
group B, there were 217 subjects with some degree of PE (category I,
109 subjects [50.2%]; category II, 23 subjects [10.6%]; and
category III, 85 subjects [39.2%]).
age group A, men < 50 years of age who were in category III (PSE or
PSE-predominant PE) predominated (34 of 53 subjects; 64.2%). In age
group B, men > 50 years of age who were in category I (CLE or
CLE-predominant PE) predominated (109 of 217 subjects;