We report the first case of myopericarditis
after triple vaccination against diphtheria, tetanus, and poliovirus in
a young adult. He presented with fever, acute chest pain, and diffuse
ST-segment elevation 2 days after vaccination. Two-dimensional
echocardiography findings were normal. Endomyocardial biopsy showed
interstitial edema with diapedesis of erythrocytes. Laboratory findings
showed inflammatory syndrome and elevated circulating immune complexes.
He recovered within a few days with high-dose aspirin treatment and was
without complications at 3-month follow-up. We discuss the different
hypotheses for infective or hypersensitivity myocarditis.