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Severe Immune Hemolytic Anemia in Disseminated Tuberculosis With Response to Antituberculosis Therapy*

Ping-Hung Kuo, MD; Pan-Chyr Yang, MD, PhD; Shoo-Shown Kuo, MD, FCCP; Kwen-Tay Luh, MD, FCCP
Author and Funding Information

*From the Departments of Internal Medicine (Drs. P.-H. Kuo and Yang) and Laboratory Medicine (Drs. S.-S. Kuo and Luh), National Taiwan University Hospital, Taipei, Taiwan.

Correspondence to: Kwen-Tay Luh, MD, FCCP, Department of Laboratory Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Rd, Taipei, Taiwan; e-mail: luhkt@ha.mc.ntu.edu.tw



Chest. 2001;119(6):1961-1963. doi:10.1378/chest.119.6.1961
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Severe hemolytic anemia in patients with disseminated tuberculosis is exceedingly rare. We report an episode of Coombs’-positive hemolytic anemia in a previously healthy young man with miliary tuberculosis, resulting in a hemoglobin level of 5 g/dL and an undetectable haptoglobin level. The patient responded well to treatment with antituberculosis drugs, and the results of the direct Coombs’ test became negative without the need of blood transfusion or steroid therapy.


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