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Influenza Pneumonia in Thoracic Organ Transplant Recipients : What Can We Do to Avoid It?

Malek G. Massad, MD, FCCP; Allan M. Ramirez, MD
Author and Funding Information

Affiliations: Chicago, IL 
 ,  Dr. Massad is Director, Heart and Lung Transplant Program, and Dr. Ramirez is Fellow, Section of Respiratory and Critical Care, University of Illinois at Chicago, Chicago, IL.

Correspondence to: Malek G. Massad, MD, FCCP, Division of Cardiothoracic Surgery (MC958), University of Illinois at Chicago, 840 South Wood St, CSB Suite 417, Chicago, IL 60612; e-mail: mmassad@uic.edu



Chest. 2001;119(4):997-999. doi:10.1378/chest.119.4.997
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It would seem common sense to assume that the occurrence of influenza pneumonia among thoracic organ transplant recipients would be at least as frequent as in the general population, if not more, because of their immunosuppressed state. Yet, there has been only a handful or so of cases reported.12 In this issue of CHEST (see page 1277), Garantziotis et al report on three adult lung transplant recipients who developed influenza pneumonia that was followed, in all patients, by a persistent decline in pulmonary function. This issue is important because more and more data are accumulating to indicate that bronchiolitis obliterans syndrome may occur among lung transplant recipients, not only following cytomegalovirus (CMV) viral respiratory infections but also following non-CMV viral respiratory infections.4 In many cases, these were associated with permanent impairment of lung function and death.

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