0
Selected Reports |

Bilateral Phrenic Paralysis in a Patient With Systemic Lupus Erythematosus*

Karen Hardy, MD, FCCP; Isabelle Herry, MD; Valérie Attali, MD; Jacques Cadranel, MD, PhD; Thomas Similowski, MD, PhD
Author and Funding Information

*From the Service de Pneumologie (Dr. Hardy), Centre Hospitalier le Raincy-Montfermeil; Service de Pneumologie (Drs. Herry and Cadranel), Hôpital Tenon; Service de Pneumologie (Dr. Attali), Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique - Hôpitaux de Paris; and UPRES EA 2397 (Dr. Similowski), Université Pierre et Marie Curie, Paris VI, France.

Correspondence to: Thomas Similowski, MD, PhD, Laboratoire de Physiopathologie Respiratoire, Service de Pneumologie et de Réanimation Groupe Hospitalier Pitié-Salpêtrière, 47–83, Bd de l’Hôpital, 75651 Paris Cedex 13, France; e-mail: thomas.similowski@psl.ap-hop-paris.fr



Chest. 2001;119(4):1274-1277. doi:10.1378/chest.119.4.1274
Text Size: A A A
Published online

Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. They include respiratory muscle abnormalities, which have been implicated in the pathogenesis of the “shrinking lung syndrome” (SLS). We report the case of a patient with this syndrome, in whom diaphragmatic paralysis due to demyelinating phrenic lesions was diagnosed at the same time as SLE. Follow-up studies showed a favorable clinical and diaphragmatic outcome with corticosteroid therapy, but little change in spirometry. It is concluded that severe diaphragm palsy is possibly due to phrenic nerve lesions in SLE, and that the link between diaphragm dysfunction and the SLS is probably not a straightforward one.

Figures in this Article

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543