We describe a rare case of a 29-year-old woman with chronic
eosinophilic pneumonia (CEP) presenting with massive bilateral pleural
effusion leading to respiratory failure, a complication that was not
reported before with CEP. The patient was successfully managed with
ventilatory support and steroid therapy. On long-term follow-up, she
remained well, receiving a low maintenance dose of prednisone without
evidence of relapse of the disease.