Effective host defense against bacterial infection is dependent on
the activation and recruitment of phagocytic cells. The initiation,
maintenance, and resolution of this inflammatory response in the
setting of bacterial pneumonia is dependent on the expression of
cytokines. As the complexities of the host-pathogen interaction are
further dissected and unraveled, immunologic manipulation of cytokine
expression will likely become an important adjuvant therapy in the
treatment of serious lung infections.