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Antithrombotic Agents in Coronary Artery Disease

John A. Cairns, MD, Chair; Pierre Théroux, MD; H. Daniel Lewis, Jr., MD; Michael Ezekowitz, MD, FCCP; Thomas W. Meade, DM
Author and Funding Information

Correspondence to: John A. Cairns, MD, Faculty of Medicine, University of British Columbia, 317-2194 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3.



Chest. 2001;119(1_suppl):228S-252S. doi:10.1378/chest.119.1_suppl.228S
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This article discusses the clinical syndromes of coronary ischemia under the major headings of acute myocardial infarction (AMI), unstable angina, primary prevention, and chronic coronary artery disease. In each section, the greatest weight is given to randomized controlled trials and to overviews of them. Although the overviews give a broad summary picture, they do not provide the immediacy and more direct relevance of individual, large, well-designed clinical trials with unequivocal results. Details of the major trials provide the reader with a sense of the sorts of patients under study and the potential generalizability of the results to the reader’s own patients. This article gives greater emphasis to relatively recent evidence, omitting details of individual trials provided in earlier editions of this consensus conference. The summaries and recommendations are based on all available evidence, whether or not it is discussed in detail in this article.

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    Print ISSN: 0012-3692
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