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Editorials |

Lightning Can Strike Twice : Second Primary Lung Cancers

Ronald B. Ponn, MD, FCCP
Author and Funding Information

Yale-New Haven Hospital New Haven, CT; Dr. Ponn is Assistant Clinical Professor and Associate Section Chief, Cardiothoracic Surgery, Yale-New Haven Hospital and the Hospital of St. Raphael.

Correspondence to: Ronald M. Ponn, MD, FCCP, Cardiothoracic Surgery, Yale-New Haven Hospital and the Hospital of St. Raphael, 330 Orchard St, New Haven, CT 06511



Chest. 2000;118(6):1526-1529. doi:10.1378/chest.118.6.1526-a
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Most patients with non-small cell lung cancer (NSCLC) present at an advanced stage and are incurable by current treatment modalities. A smaller group, 20 to 25% of cases, in whom cancer is detected while it is still localized, have a reasonable chance of long-term survival. A majority of patients with stage I and a significant minority of those with stage II NSCLC achieve cancer-free survival for > 5 years after complete resection. Recurrence of the primary tumor is rarely amenable to curative therapy. In contrast, patients with localized second primary lung cancers who are physiologically able to undergo complete resection may benefit from reoperation.

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lung cancer

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