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New Insights Into the Temporal Pattern of Hypoxemia in COPD

Michael Cutaia, MD, FCCP
Author and Funding Information

Philadelphia, PA Dr. Cutaia is from the Pulmonary Section, VA Medical Center, University of Pennsylvania.

Correspondence to: Michael Cutaia, MD, FCCP, Woodland and University Ave, Research Service, Philadelphia, PA 19104; e-mail: mcutaia@mail.med.upenn.edu



Chest. 2000;118(6):1521-1522. doi:10.1378/chest.118.6.1521
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The life-preserving benefits of long-term oxygen therapy (LTOT) were established nearly 2 decades ago.12 One cannot overemphasize the fact that LTOT is the only treatment that has a positive impact on mortality in COPD patients. Pulmonologists are well versed in the benefits of LTOT, and recognize the importance of identifying hypoxemic patients and instituting LTOT. The criteria for implementation of LTOT are well defined. Therefore, it is somewhat surprising that there has been little interest in building on the findings of the original studies that documented the survival benefit of LTOT. Acceptance of LTOT has lead to a complacency that there is nothing more to learn on this topic, especially in the molecular biology era.

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