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Editorials |

Deep Vein Thrombosis and Pulmonary Embolism : A Single Disease Entity With Different Risk Factors?

Arnaud Perrier, MD, FCCP
Author and Funding Information

Affiliations: Geneva, Switzerland 
 ,  Dr. Perrier is from Medical Clinic 1, Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland.

Correspondence to: Arnaud Perrier, MD, FCCP, Medical Clinic 1, Geneva University Hospital, 24, rue Micheli-du-Crest, CH-1211 Geneva 14, Switzerland; e-mail: Arnaud.Perrier@medecine.unige.ch



Chest. 2000;118(5):1234-1236. doi:10.1378/chest.118.5.1234
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In recent years, deep vein thrombosis and pulmonary embolism, its major complication, have been increasingly considered as a single disease entity, namely venous thromboembolism. Indeed, both autopsic1 and clinical studies2 have shown that approximately 90% of pulmonary emboli arise from the deep veins of the lower limbs. Moreover, an asymptomatic pulmonary embolism can be found in about half the patients presenting with a symptomatic proximal deep vein thrombosis.3 Finally, deep vein thrombosis and pulmonary embolism share many risk factors, such as age, major surgery or trauma, cancer, immobilization, pregnancy, oral contraceptives, and hormone replacement therapy.

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    Print ISSN: 0012-3692
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