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Editorials |

Pneumocystis Pneumonia : Miles to Go

Henry Masur, MD; James H. Shelhamer, MD, FCCP
Author and Funding Information

Affiliations: Bethesda, MD 
 ,  Dr. Masur is Chief, Critical Care Medicine, and Dr. Shelhamer is Deputy Chief, Critical Care Medicine, National Institutes of Health, Clinical Center.

Correspondence to: Henry Masur, MD, National Institutes of Health, Clinical Center, Critical Care Medicine Department, 10 Center Dr, Room 7D43, Bethesda, MD 20892-1662; e-mail: hmasur@cc.nih.gov



Chest. 2000;118(3):575-577. doi:10.1378/chest.118.3.575
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When Pneumocystis carinii pneumonia (PCP) appeared in previously healthy patients in the late 1970s, clinicians quickly recognized that a new form of immunosuppression had occurred, and, thus, PCP was the most prominent feature in the initial reports of the syndrome now designated as AIDS. Clinicians promptly recognized that the PCP they were seeing in patients with AIDS differed in important ways from the PCP that was seen in other patient populations. In fact, most opportunistic pathogens such as Candida, cytomegalovirus, and herpes simplex caused somewhat different manifestations in AIDS patients compared to patients who had cancer or had undergone organ transplantation.

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