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Clinical Investigations: HEMOPTYSIS |

Seasonal Variation in Cryptogenic and Noncryptogenic Hemoptysis Hospitalizations in France*

Fabrice Boulay, MD; Frédéric Berthier, MD; Olivier Sisteron, MD; Yves Gendreike, MD; Bruno Blaive, MD
Author and Funding Information

*From the Departments of Public Health and Medical Information (Drs. Boulay, Berthier, Sisteron, and Gendreike) and Respiratory Medicine (Dr. Blaive), Nice Teaching Hospital, Nice, France.

Correspondence to: Fabrice Boulay, MD, Département d’Information Médicale, CHU de Nice BP 1179, 06003 Nice, Cedex 1, France; e-mail: boulayf@hotmail.com



Chest. 2000;118(2):440-444. doi:10.1378/chest.118.2.440
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Study objective: To determine the potential role of seasonality in hospitalizations for cryptogenic and noncryptogenic hemoptysis in the French population.

Design: Retrospective analysis of hospital discharge data from a National Register.

Setting: All 29 French university hospitals, between July 1, 1994, and June 30, 1997.

Patients: Two thousand six hundred seventy-seven and 3,672 adult hospitalizations for cryptogenic and other hemoptysis, respectively.

Measurements: Cumulative monthly averages were determined, expressed as the percentage above or below the average monthly value during the entire study period.

Results: The distribution of cumulative monthly hospitalizations for cryptogenic hemoptysis peaked in March (32% above the average) and was lowest in summer (30% below the average; p < 0.001). Hospitalizations for noncryptogenic hemoptysis followed a similar seasonal pattern (p < 0.001). In the 16- to 34-year-old individuals, cryptogenic hemoptysis, compared with noncryptogenic hemoptysis, showed a higher incidence with a larger seasonal amplitude (p < 0.001).

Conclusions: A better understanding of the fundamental pathophysiologic mechanisms underlying this respiratory and hemorrhagic condition may be helpful in developing preventive measures, especially in patients with a risk of recurrence.

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